Kristina Yucius - Concepedia

Author

Kristina Yucius

Alnylam Pharmaceuticals (United States)

Also Known As

K. Yucius, Kristina Yucius

Publications

914

Citations

H-Index

Concepts

All Affiliations

Alnylam Pharmaceuticals (United States)

About

Kristina Yucius is an author at Alnylam Pharmaceuticals (United States) specializing in cell biology, medicine, and gene delivery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	486
2	Cell Biology	3	3	486
3	Engineering	1	1	135
4	Natural Sciences	1	1	180
5	Biochemistry	1	1	180

Kristina Yucius

Publications

903

Citations

H-Index

Page 1

	Year	Citations
siRNA Conjugates Carrying Sequentially Assembled Trivalent <i>N-</i>Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing <i>In Vivo</i> in Hepatocytes Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair, ACS Chemical Biology	2015	206
Hepatocyte‐Specific Delivery of siRNAs Conjugated to Novel Non‐nucleosidic Trivalent <i>N</i>‐Acetylgalactosamine Elicits Robust Gene Silencing in Vivo Kallanthottathil G. Rajeev, Jayaprakash K. Nair, Muthusamy Jayaraman, ChemBioChem Bioorganic ChemistryMolecular BiologyGene DeliveryChemical BiologyMedicinal Chemistry	2015	180
A rapid two-step method for isolation of functional primary mouse hepatocytes: cell characterization and asialoglycoprotein receptor based assay development Mariano Severgnini, Jennifer Sherman, Alfica Sehgal, Cytotechnology Autoimmune DiseaseHepatologyFunctional Primary MouseRapid Two-step MethodLiver Physiology	2011	171
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells Tatiana I. Novobrantseva, Anna Borodovsky, Jamie Wong, Molecular Therapy — Nucleic Acids NanotherapeuticsEngineeringGeneticsImmunologyImmunotherapeutics	2012	135
Evaluation of GalNAc-siRNA Conjugate Activity in Pre-clinical Animal Models with Reduced Asialoglycoprotein Receptor Expression Jennifer L. S. Willoughby, Amy Chan, Alfica Sehgal, Molecular Therapy	2017	106
Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia Gravis Linda L. Kusner, Kristina Yucius, Manjistha Sengupta, Molecular Therapy — Methods & Clinical Development	2019	52
Metabolically Stable Anomeric Linkages Containing GalNAc–siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways Kandasamy Pachamuthu, S. Mori, Shigeo Matsuda, Journal of Medicinal Chemistry	2023	27
Aln-CC5, an Investigational RNAi Therapeutic Targeting C5 for Complement Inhibition Anna Borodovsky, Kristina Yucius, Andrew Sprague, Blood	2014	14
Development Of RNAi Therapeutics Targeting The Complement Pathway Anna Borodovsky, Kristina Yucius, Andrew Sprague, Blood	2013	12

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