Yukiko Sekiguchi

Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification

Mitsuhiro Iwamoto, Yukiko Sekiguchi, Kensuke Nakamura et al. · PLoS ONE · 2018 · 24 citations · Full text

Engineering, One-pot Transglycosylation, Glycobiology +18

Discovery of CS-2100, a potent, orally active and S1P3-sparing S1P1 agonist

Tsuyoshi Nakamura, Masayoshi Asano, Yukiko Sekiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 23 citations · Full text

Medicinal Chemistry, G Protein-coupled Receptor, Medicine +7

Synthesis and evaluation of CS-2100, a potent, orally active and S1P3- sparing S1P1 agonist

Tsuyoshi Nakamura, Masayoshi Asano, Yukiko Sekiguchi et al. · European Journal of Medicinal Chemistry · 2012 · 17 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +6

Efficient and versatile synthesis of 5-O-acylquinic acids with a direct esterification using a p-methoxybenzyl quinate as a key intermediate

Kin‐ichi Oyama, Noriyuki Watanabe, Tomomi Yamada et al. · Tetrahedron · 2014 · 12 citations

5-O-acylquinic Acids, Engineering, Direct Esterification +6

Synthesis and SAR of 1,3-thiazolyl thiophene and pyridine derivatives as potent, orally active and S1P3-sparing S1P1 agonists

Masayoshi Asano, Tsuyoshi Nakamura, Yukiko Sekiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 10 citations · Full text