PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy

Christian Riehle, Adam R. Wende, Vlad G. Zaha, +13

Circulation Research

Inducible Overexpression of GLUT1 Prevents Mitochondrial Dysfunction and Attenuates Structural Remodeling in Pressure Overload but Does Not Prevent Left Ventricular Dysfunction

Renata O. Pereira, Adam R. Wende, Curtis D. Olsen, +5

Journal of the American Heart Association

Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth

Yi Zhu, Karla Maria Pereira Pires, Kevin J. Whitehead, +9

PLoS ONE

Cardiac MuscleCardiac Progenitor CellsCardiomyocyte Mtor DeficiencyCardiac RegenerationCell Proliferation +19

Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction

Sandra Sena, Ping Hu, Dongfang Zhang, +6

Journal of Molecular and Cellular Cardiology

Metabolic SyndromeInsulin SignalingHeart FailureCardiovascular DiseaseMitochondrial Function +8

UCP3 Regulates Cardiac Efficiency and Mitochondrial Coupling in High Fat–Fed Mice but Not in Leptin-Deficient Mice

Sihem Boudina, Yong Hwan Han, Shaobo Pei, +6

Diabetes

Nitro-oleic acid protects against endotoxin-induced endotoxemia and multiorgan injury in mice

Haiping Wang, Haiying Liu, Zhunjun Jia, +4

American Journal of Physiology-Renal Physiology

Endotoxin-induced EndotoxemiaNitro-oleic Acid ProtectsLipid PeroxidationImmunologyRenal Inflammation +19

Maintaining PGC‐1α expression following pressure overload‐induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function

Renata O. Pereira, Adam R. Wende, Ashley Crum, +6

The FASEB Journal

Cardiac MusclePgc‐1α ExpressionHeart FailureGeneticsPressure Overload Hypertrophy +26

GLUT1 deficiency in cardiomyocytes does not accelerate the transition from compensated hypertrophy to heart failure

Renata O. Pereira, Adam R. Wende, Curtis D. Olsen, +5

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyHeart FailureMolecular PhysiologyCardiovascular Disease +8

Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome

Olesya Ilkun, Nicole Wilde, Joseph Tuinei, +8

Journal of Molecular and Cellular Cardiology

Metabolic SyndromeMitochondrial FunctionBiochemistryMitochondrial EnergeticsMedicine +11

Phosphoinositide dependent protein kinase 1 is required for exercise-induced cardiac hypertrophy but not the associated mitochondrial adaptations

Jung Hyun Noh, Adam R. Wende, Curtis D. Olsen, +6

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyKinesiologyMolecular PhysiologyMitochondrial Function +11