Joseph Dukes

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

Gerald P. Linette, Edward A. Stadtmauer, Marcela V. Maus et al. · Blood · 2013 · 1.2K citations

Life Sciences, Immunology, Oncology +16

Identification of a Titin-Derived HLA-A1–Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3–Directed T Cells

Brian Cameron, Andrew B. Gerry, Joseph Dukes et al. · Science Translational Medicine · 2013 · 677 citations

Life Sciences, Immunology, Molecular Biology +17

Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy

Marine C. C. Raman, P.J. Rizkallah, Ruth Simmons et al. · Scientific Reports · 2016 · 108 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules

Jane Harper, Katherine J. Adams, Giovanna Bossi et al. · PLoS ONE · 2018 · 83 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells

Joseph Dukes, Laura Pamela Fish, Judith D. Richardson et al. · Molecular Biology of the Cell · 2011 · 67 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16