Concepedia

Jacob P. Mahoney

JP

Statistics

Publications

8

Citations

2.3K

H-Index

8

Active since

2013

Affiliations

University of Michigan(Current)

University of California San Diego

Vrije Universiteit Brussel

Stanford University

VIB-VUB Center for Structural Biology

Jacob P. Mahoney is an author at University of Michigan specializing in signal transduction, molecular biology, and ligand binding.

ORCID

Publications per year

2013–2022

8

Publications

8

Conformational biosensors reveal GPCR signalling from endosomes

Roshanak Irannejad, Jin C. Tomshine, Jon R. Tomshine et al. · Nature · 2013 · 840 citations · Full text

, , +12

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

A. Thomsen, Bianca Plouffe, Thomas J. Cahill et al. · Cell · 2016 · 569 citations · Full text

, , +6

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Brian T. DeVree, Jacob P. Mahoney, Gisselle A. Vélez-Ruiz et al. · Nature · 2016 · 298 citations · Full text

, , +14

Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex

Anthony H. Nguyen, A. Thomsen, Thomas J. Cahill et al. · Nature Structural & Molecular Biology · 2019 · 227 citations · Full text

, , +11

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist

Matthieu Masureel, Yaozhong Zou, Louis-Philippe Picard et al. · Nature Chemical Biology · 2018 · 203 citations · Full text

, , +14

1–5 of 8