Zhi‐Xin Lei

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 148 citations

Engineering, Genome Surgery, Genetic Engineering +10

Mitochondrial base editor induces substantial nuclear off-target mutations

Zhi‐Xin Lei, Haowei Meng, Lulu Liu et al. · Nature · 2022 · 109 citations

Mitochondrial Base Editor, Mitochondrial Biogenesis, Mitochondrial Function +7

Detect-seq reveals out-of-protospacer editing and target-strand editing by cytosine base editors

Zhi‐Xin Lei, Haowei Meng, Zhicong Lv et al. · Nature Methods · 2021 · 56 citations

Target-strand Editing, Molecular Biological Method, Natural Sciences +10

A Radiolabeling‐Free, qPCR‐Based Method for Locus‐Specific Pseudouridine Detection

Zhi‐Xin Lei, Chengqi Yi · Angewandte Chemie International Edition · 2017 · 53 citations

ψ Residues, Engineering, Genetics +21

Indium−Sulfur Supertetrahedral Clusters Integrated with a Metal Complex of 1,10-Phenanthroline

Zhi‐Xin Lei, Qin‐Yu Zhu, Wen Luo et al. · Inorganic Chemistry · 2010 · 44 citations