Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons

Peter G. Hendrickson, Jessie Dorais, Edward J. Grow, +12

Nature Genetics

Knockout MouseHuman Dux4GeneticsGenomic MechanismGenetic Mechanism +9

Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility

Saher Sue Hammoud, Jahnvi Purwar, Christian Pflueger, +2

Fertility and Sterility

SpermatogenesisChromatinInfertilityFertilityImprinted Loci +12

Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility

Timothy G. Jenkins, Kenneth I. Aston, Christian Pflueger, +2

PLoS Genetics

Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution

Charles A. Herring, Rebecca K. Simmons, Saskia Freytag, +18

Cell

A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs

Christian Pflueger, Dennis Eng Kiat Tan, Tessa Swain, +6

Genome Research

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationMolecular Biology +15

Synthetic memory circuits for stable cell reprogramming in plants

James P. B. Lloyd, Florence Ly, Patrick Gong, +7

Nature Biotechnology

Synthetic Memory CircuitsEngineeringMedicineBiotechnologySynthetic Biology +7

Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription

Saravanan Ramakrishnan, Srijana Pokhrel, Sowmiya Palani, +5

Nature Communications

A modular dCas9-based recruitment platform for combinatorial epigenome editing

Tessa Swain, Christian Pflueger, Saskia Freytag, +5

Nucleic Acids Research

GeneticsMolecular BiologyTargeted EditingEpigeneticsTranscriptional Regulation +18

Synthetic Epigenetic Reprogramming of Mesenchymal to Epithelial States Using the CRISPR/dCas9 Platform in Triple Negative Breast Cancer

Charlene Waryah, Joseph Cursons, Momeneh Foroutan, +18

Advanced Science

RNA variant assessment using transactivation and transdifferentiation

Emmylou C Nicolas-Martinez, O.F. Robinson, Christian Pflueger, +25

The American Journal of Human Genetics