Erwin Coesemans

Pharmacological Profile of JNJ-27141491 [(S)-3-[3,4-Difluorophenyl)-propyl]-5-isoxazol-5-yl-2-thioxo-2,3-dihydro-1 H-imidazole-4-carboxyl Acid Methyl Ester], as a Noncompetitive and Orally Active Antagonist of the Human Chemokine Receptor CCR2

Mieke Buntinx, Bart Hermans, Jan Goossens et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 26 citations

Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor

Bart Kesteleyn, Jean‐François Bonfanti, Dorothée Bardiot et al. · Journal of Medicinal Chemistry · 2024 · 25 citations

Characterization of a dengue NS4B inhibitor originating from an HCV small molecule library

Ilane Hernández‐Morales, Peggy Geluykens, Marleen Clynhens et al. · Antiviral Research · 2017 · 23 citations

Medicine, Arbovirus, Antiviral Therapy +7

Design and Synthesis of a Series of Piperazine‐1‐carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species

Isabelle François, Karin Thevissen, Klaartje Pellens et al. · ChemMedChem · 2009 · 19 citations

Bioorganic Chemistry, Pharmaceutical Chemistry, Redox Biology +16

Synthesis and Biological Evaluation of 1,2,4-Triazinylphenylalkylthiazolecarboxylic Acid Esters as Cytokine-Inhibiting Antedrugs with Strong Bronchodilating Effects in an Animal Model of Asthma

Eddy Freyne, Jean Lacrampe, Frederik Deroose et al. · Journal of Medicinal Chemistry · 2004 · 19 citations

Inflammation, Asthma, Medicinal Chemistry +15