Irene Vuu

Absorption, metabolism and excretion of [14C]-sotorasib in healthy male subjects: characterization of metabolites and a minor albumin-sotorasib conjugate

Irene Vuu, Upendra P. Dahal, Zhe Wang et al. · Cancer Chemotherapy and Pharmacology · 2022 · 23 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +11

Validation of an LC–MS/MS method for the determination of sotorasib, a KRAS ^G12C inhibitor, in human plasma

Philip Wong, Anna Akrami, Brett E. Houk et al. · Bioanalysis · 2022 · 17 citations

Medicine, Oncology, Pharmacology +17

Phase 1 clinical trial of AMG 340, a prostate-specific membrane antigen (PSMA)-targeted T-cell engager with a novel low-affinity CD3 binding domain designed to mitigate toxicity for the treatment of metastatic castration-resistant prostate cancer (mCRPC).

Gerald S. Falchook, Meredith McKean, William K. Kelly et al. · Journal of Clinical Oncology · 2024 · 16 citations

Medicine, Oncology, Pharmacology +17

Intravenous Topiramate: Pharmacokinetics in Dogs with Naturally Occurring Epilepsy

Irene Vuu, Lisa D. Coles, Patricia D. Maglalang et al. · Frontiers in Veterinary Science · 2016 · 14 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +12