Joshua C. Horan

The Practical Synthesis of a Novel and Highly Potent Analogue of Bryostatin

Paul A. Wender, Jeremy L. Baryza, Chad Bennett et al. · Journal of the American Chemical Society · 2002 · 154 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

The Clinically-tested S1P Receptor Agonists, FTY720 and BAF312, Demonstrate Subtype-Specific Bradycardia (S1P1) and Hypertension (S1P3) in Rat

Ryan M. Fryer, Akalushi Muthukumarana, Paul C. Harrison et al. · PLoS ONE · 2012 · 79 citations · Full text

Medicine, Pharmacology, Physiology +17

Function Oriented Synthesis: The Design, Synthesis, PKC Binding and Translocation Activity of a New Bryostatin Analog

Paul A. Wender, Jeremy L. Baryza, Stacey E. Brenner et al. · Current Drug Discovery Technologies · 2004 · 51 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations

Alexander Drilon, Joshua C. Horan, Anupong Tangpeerachaikul et al. · Cancer Discovery · 2022 · 49 citations · Full text

Medicine, Oncology, Pharmacology +15

NVL-655 Is a Selective and Brain-Penetrant Inhibitor of Diverse ALK-Mutant Oncoproteins, Including Lorlatinib-Resistant Compound Mutations

Joshua C. Horan, Anupong Tangpeerachaikul, Aurélie Swalduz et al. · Cancer Discovery · 2024 · 45 citations · Full text

Medicine, Oncology, Pharmacology +13