F M Lenaerts

Delay of castor oil diarrhoea in rats: a new way to evaluate inhibitors of prostaglandin biosynthesis

F. Awouters, C. J. E. Niemegeers, F M Lenaerts et al. · Journal of Pharmacy and Pharmacology · 1978 · 314 citations

Gastrointestinal Pharmacology, Pharmacotherapy, Experimental Pharmacology +18

Is it possible to predict the clinical effects of neuroleptic drugs (major tranquillizers) from animal data? IV. An improved experimental design for measuring the inhibitory effects of neuroleptic drugs on amphetamine-or apomorphine-induced "Cheroing" and "agitation" in rats.

Paul A. J. Janssen, C. J. E. Niemegeers, K H Schellekens et al. · PubMed · 1967 · 134 citations

Psychoactive Drug, Pharmacological Study, Psychiatry +13

Etomidate, R-(+)-ethyl-1-( -methyl-benzyl)imidazole-5-carboxylate (R 16659), a potent, short-acting and relatively atoxic intravenous hypnotic agent in rats.

Paul A. J. Janssen, C. J. E. Niemegeers, K H Schellekens et al. · PubMed · 1971 · 89 citations

Molecular Pharmacology, Medicinal Chemistry, Psychoactive Drug +9

The pharmacology of penfluridol (R 16341) a new potent and orally long-acting neuroleptic drug

Paul A. J. Janssen, C. J. E. Niemegeers, K H Schellekens et al. · European Journal of Pharmacology · 1970 · 79 citations

Neuromodulation (Medicine), Medicine, Long-acting Neuroleptic Drug +10

Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 1: in vivo oral pharmacology and acute toxicity. Comparison with morphine, codeine, diphenoxylate and difenoxine.

C. J. E. Niemegeers, F M Lenaerts, Paul A. J. Janssen · PubMed · 1974 · 65 citations

Molecular Pharmacology, Antidiarrheal Agent, Gastrointestinal Pharmacology +8