Maja K. Blake

SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment

Patrick M. O’Connell, Sean Hyslop, Maja K. Blake et al. · The Journal of Immunology · 2020 · 104 citations · Full text

Life Sciences, Immunology, Oncology +17

Targeted inhibition of the deubiquitinating enzymes, <scp>USP</scp>14 and <scp>UCHL</scp>5, induces proteotoxic stress and apoptosis in <scp>W</scp>aldenström macroglobulinaemia tumour cells

Kasyapa S. Chitta, Aneel Paulus, Sharoon Akhtar et al. · British Journal of Haematology · 2015 · 62 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Waldenstrom macroglobulinemia cells devoid of BTKC481S or CXCR4WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment

Aneel Paulus, Sharoon Akhtar, Hamza Yousaf et al. · Blood Cancer Journal · 2017 · 54 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

ERAP1 deficient mice have reduced Type 1 regulatory T cells and develop skeletal and intestinal features of Ankylosing Spondylitis

Yuliya Pepelyayeva, David P. W. Rastall, Yasser A. Aldhamen et al. · Scientific Reports · 2018 · 44 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

SLAMF7 Is a Critical Negative Regulator of IFN-α–Mediated CXCL10 Production in Chronic HIV Infection

Patrick M. O’Connell, Yuliya Pepelyayeva, Maja K. Blake et al. · The Journal of Immunology · 2018 · 43 citations · Full text

Life Sciences, Immunology, Molecular Biology +15