Lindsey A. Carfrae

A Deep Learning Approach to Antibiotic Discovery

Jonathan Stokes, Kevin Yang, Kyle Swanson et al. · Cell · 2020 · 2.2K citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +14

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

Brian Alcock, William Huynh, Romeo Chalil et al. · Nucleic Acids Research · 2022 · 2.1K citations · Full text

Life Sciences, Bioinformatics, Microbiology +17

Overcoming mcr-1 mediated colistin resistance with colistin in combination with other antibiotics

Craig R. MacNair, Jonathan Stokes, Lindsey A. Carfrae et al. · Nature Communications · 2018 · 292 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Inhibiting fatty acid synthesis overcomes colistin resistance

Lindsey A. Carfrae, Kenneth Rachwalski, Shawn French et al. · Nature Microbiology · 2023 · 79 citations

Life Sciences, Biochemistry, Biotechnology +11

Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens

Lindsey A. Carfrae, Craig R. MacNair, Christopher M. Brown et al. · Nature Microbiology · 2019 · 49 citations

Life Sciences, Infectious Diseases, Microbiology +17