Charles A. Blum

Crystallographic structure of a small molecule SIRT1 activator-enzyme complex

Han Dai, April Case, Thomas V. Riera et al. · Nature Communications · 2015 · 197 citations · Full text

Discovery of Thieno[3,2-<i>d</i>]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3

Jeremy S. Disch, Ghotas Evindar, Cynthia H. Chiu et al. · Journal of Medicinal Chemistry · 2013 · 190 citations · Full text

Bis-heteroannulation. 15. Enantiospecific syntheses of (+)- and (-)-norsecurinine

Peter A. Jacobi, Charles A. Blum, Robert Desimone et al. · Journal of the American Chemical Society · 1991 · 65 citations

Molecular Sciences, Engineering, Chemical Analysis +14

The conversion of car☐ylic acids to keto phosphorane precursors of 1,2,3-vicinal tricarbonyl compounds

Harry H. Wasserman, David S. Ennis, Charles A. Blum et al. · Tetrahedron Letters · 1992 · 44 citations

Design, Synthesis, and Biological Evaluation of Substituted 2-Cyclohexyl-4-phenyl-1<i>H</i>-imidazoles:  Potent and Selective Neuropeptide Y Y5-Receptor Antagonists

Charles A. Blum, Xiaozhang Zheng, Stéphane De Lombaert · Journal of Medicinal Chemistry · 2004 · 43 citations

Medicinal Chemistry, Biochemistry, Functional Selectivity +15