Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells

Liam Chung, Erik Thiele Orberg, Abby L. Geis, +22

Cell Host & Microbe

InflammationMicrobial ToxinColonic Epithelial CellsPathogenesisPathology +7

Divergent immune responses to synthetic and biological scaffolds

Kaitlyn Sadtler, Matthew T. Wolf, Sudipto Ganguly, +6

Biomaterials

Divergent Immune ResponsesMedicineImmunologySynthetic BiologyImmunomodulation +3

IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis

Heather J. Faust, Hong Zhang, Jin Han, +13

Journal of Clinical Investigation

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic

Sarah Tomkovich, Christine M. Dejea, Kathryn Winglee, +23

Journal of Clinical Investigation

BiofilmsDysbiosisHealthy SubjectsMucosal ImmunologyPathology +11

The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis

Erik Thiele Orberg, Hongni Fan, Ada Tam, +12

Mucosal Immunology

Myeloid Immune SignatureDysbiosisMucosal ImmunologyPathogenesisImmunology +6

Interleukin 17 and senescent cells regulate the foreign body response to synthetic material implants in mice and humans

Liam Chung, David R. Maestas, Andriana Lebid, +17

Science Translational Medicine

Interleukin-36γ–producing macrophages drive IL-17–mediated fibrosis

Sven D. Sommerfeld, Christopher Cherry, Liam Chung, +10

Science Immunology

Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A

June L. Chan, Shaoguang Wu, Abby L. Geis, +12

Mucosal Immunology

Bacterial-Driven Inflammation and Mutant <i>BRAF</i> Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy

Christina E. DeStefano Shields, James R. White, Liam Chung, +19

Cancer Discovery

YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response

Andriana Lebid, Liam Chung, Drew M. Pardoll, +1

Frontiers in Immunology