Naomy Bernstein

Discovery of <i>N</i>-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide (MGCD0103), an Orally Active Histone Deacetylase Inhibitor

Nancy Zhou, Oscar Moradei, Stéphane Raeppel et al. · Journal of Medicinal Chemistry · 2008 · 108 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Structurally Simple Trichostatin A-Like Straight Chain Hydroxamates as Potent Histone Deacetylase Inhibitors

Soon Hyung Woo, Sylvie Fréchette, Elie Abou Khalil et al. · Journal of Medicinal Chemistry · 2002 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases

Stephen Claridge, Franck Raeppel, Marie‐Claude Granger et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors

Ljubomir Isakovic, Oscar M. Saavedra, David B. Llewellyn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +8

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes

Oscar M. Saavedra, Ljubomir Isakovic, David B. Llewellyn et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 49 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8