Christopher Naylor

3D-QSAR of angiotensin-converting enzyme and thermolysin inhibitors: a comparison of CoMFA models based on deduced and experimentally determined active site geometries

Scott A. DePriest, Dorica Mayer, Christopher Naylor et al. · Journal of the American Chemical Society · 1993 · 168 citations

Pharmaceutical Science, Altmetric Attention Score, Pharmacotherapy +21

A unique geometry of the active site of angiotensin-converting enzyme consistent with structure-activity studies

Dorica Mayer, Christopher Naylor, Ioan Moţoc et al. · Journal of Computer-Aided Molecular Design · 1987 · 153 citations

Protein Chemistry, Biochemistry, Enzyme Catalysis +6

6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084):  The First Selective and Brain Penetrant 5-HT_2C Receptor Antagonist

Steven M. Bromidge, Malcolm Duckworth, Ian T. Forbes et al. · Journal of Medicinal Chemistry · 1997 · 84 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Chemical Biology +19

Synthesis and muscarinic activities of quinuclidin-3-yltriazole and -tetrazole derivatives

Harry J. Wadsworth, S. M. Jenkins, Barry S. Orlek et al. · Journal of Medicinal Chemistry · 1992 · 83 citations · Full text

Novel and Selective 5-HT_2C/2B Receptor Antagonists as Potential Anxiolytic Agents:  Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling of Substituted 1-(3-Pyridylcarbamoyl)indolines

Steven M. Bromidge, Steven Dabbs, David T. Davies et al. · Journal of Medicinal Chemistry · 1998 · 64 citations · Full text

Biological Activity, Molecular Pharmacology, Medicinal Chemistry +15