Shiew‐Mei Huang

Evaluation of Cytochrome P450 Probe Substrates Commonly Used by the Pharmaceutical Industry to Study in Vitro Drug Interactions

Rae Yuan, Soraya Madani, Xiaoxiong Wei et al. · Drug Metabolism and Disposition · 2002 · 324 citations

Medicine, Pharmacokinetics, Pharmacology +16

Physiologically Based Pharmacokinetic Modeling in Regulatory Science: An Update From the U.S. Food and Drug Administration’s Office of Clinical Pharmacology

Manuela Grimstein, Yuching Yang, Xinyuan Zhang et al. · Journal of Pharmaceutical Sciences · 2018 · 308 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Effect of St John's wort on the pharmacokinetics of fexofenadine

Zaiqi Wang, Mitchell A. Hamman, Shiew‐Mei Huang et al. · Clinical Pharmacology & Therapeutics · 2002 · 213 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

Model‐Informed Drug Development: Current US Regulatory Practice and Future Considerations

Yaning Wang, Hao Zhu, Rajanikanth Madabushi et al. · Clinical Pharmacology & Therapeutics · 2019 · 209 citations

Pharmacy, Pharmaceutical Policy, Pharmaceutical Regulation +10

Application of PBPK Modeling and Simulation for Regulatory Decision Making and Its Impact on US Prescribing Information: An Update on the 2018‐2019 Submissions to the US FDA's Office of Clinical Pharmacology

Xinyuan Zhang, Yuching Yang, Manuela Grimstein et al. · The Journal of Clinical Pharmacology · 2020 · 179 citations

Pharmacy, Pharmacokinetics, Pharmacology +15