Hao Zhu

Model‐Informed Drug Development: Current US Regulatory Practice and Future Considerations

Yaning Wang, Hao Zhu, Rajanikanth Madabushi et al. · Clinical Pharmacology & Therapeutics · 2019 · 202 citations

Consideration of a Credibility Assessment Framework in Model‐Informed Drug Development: Potential Application to Physiologically‐Based Pharmacokinetic Modeling and Simulation

Colleen Kuemmel, Yuching Yang, Xinyuan Zhang et al. · CPT Pharmacometrics & Systems Pharmacology · 2019 · 151 citations · Full text

Vandetanib for the Treatment of Symptomatic or Progressive Medullary Thyroid Cancer in Patients with Unresectable Locally Advanced or Metastatic Disease: U.S. Food and Drug Administration Drug Approval Summary

Katherine A. Thornton, Geoffrey Kim, V. Ellen Maher et al. · Clinical Cancer Research · 2012 · 147 citations

Caprelsa Tablets, U.s. Food, Medicine +11

Impact of Pharmacometric Analyses on New Drug Approval and Labelling Decisions

Joo Yeon Lee, Christine Garnett, Jogarao Gobburu et al. · Clinical Pharmacokinetics · 2011 · 146 citations

Drug Safety, Labelling Decisions, New Drug Approval +9

Connecting Hydroxychloroquine In Vitro Antiviral Activity to In Vivo Concentration for Prediction of Antiviral Effect: A Critical Step in Treating Patients With Coronavirus Disease 2019

Jianghong Fan, Xinyuan Zhang, Jiang Liu et al. · Clinical Infectious Diseases · 2020 · 76 citations · Full text

Pharmacotherapy, Vitro 50, Antiviral Drug +16