Dirk Ruesch

2-(3-Methyl-3<i>H</i>-diaziren-3-yl)ethyl 1-(1-phenylethyl)-1<i>H</i>-imidazole-5-carboxylate:  A Derivative of the Stereoselective General Anesthetic Etomidate for Photolabeling Ligand-Gated Ion Channels

S. Shaukat Husain, Michael R. Ziebell, Dirk Ruesch et al. · Journal of Medicinal Chemistry · 2003 · 85 citations · Full text

An Allosteric Coagonist Model for Propofol Effects on α1β2γ2L γ-Aminobutyric Acid Type A Receptors

Dirk Ruesch, Elena Neumann, Hinnerk Wulf et al. · Anesthesiology · 2011 · 64 citations · Full text

γ-Amino Butyric Acid Type A Receptor Mutations at β2N265 Alter Etomidate Efficacy While Preserving Basal and Agonist-dependent Activity

Rooma Desai, Dirk Ruesch, Stuart A. Forman · Anesthesiology · 2009 · 60 citations · Full text

Differential Effects of Serotonin and Dopamine on Human 5-HT_3AReceptor Kinetics: Interpretation within an Allosteric Kinetic Model

Ken Solt, Dirk Ruesch, Stuart A. Forman et al. · Journal of Neuroscience · 2007 · 48 citations · Full text

Synthesis of Trifluoromethylaryl Diazirine and Benzophenone Derivatives of Etomidate that Are Potent General Anesthetics and Effective Photolabels for Probing Sites on Ligand-Gated Ion Channels

S. Shaukat Husain, Selvanayagam Nirthanan, Dirk Ruesch et al. · Journal of Medicinal Chemistry · 2006 · 45 citations