Diana Orentas Lein

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

Thierry Dervieux, Daniel E. Furst, Diana Orentas Lein et al. · Arthritis & Rheumatism · 2004 · 334 citations

Life Sciences, Genetics, Pharmacology +17

Contribution of common polymorphisms in reduced folate carrier and ??-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis

Thierry Dervieux, Joel M. Kremer, Diana Orentas Lein et al. · Pharmacogenetics · 2004 · 161 citations

Medicine, Pharmacology, Pharmacogenetics +16

HPLC Determination of Erythrocyte Methotrexate Polyglutamates after Low-Dose Methotrexate Therapy in Patients with Rheumatoid Arthritis

Thierry Dervieux, Diana Orentas Lein, John F. Marcelletti et al. · Clinical Chemistry · 2003 · 109 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16