T Sugahara

Biosynthesis of a biologically active single peptide chain containing the human common alpha and chorionic gonadotropin beta subunits in tandem.

T Sugahara, Mary R. Pixley, Sawako Minami et al. · Proceedings of the National Academy of Sciences · 1995 · 112 citations · Full text

Protein Assembly, Glycobiology, Molecular Biology +21

Expression of Biologically Active Fusion Genes Encoding the Common α Subunit and the Follicle-stimulating Hormone β Subunit

T Sugahara, Asomi Sato, Masataka Kudo et al. · Journal of Biological Chemistry · 1996 · 73 citations · Full text

Fusing the carboxy-terminal peptide of the chorionic gonadotropin (CG) beta-subunit to the common alpha-subunit: retention of O-linked glycosylation and enhanced in vivo bioactivity of chimeric human CG.

Madoka Furuhashi, Toshihiko Shikone, Fuad Fares et al. · Molecular Endocrinology · 1995 · 55 citations · Full text

Chorionic Gonadotropin, Hcg Beta Gene, Vivo Half-life +19

Design of stable biologically active recombinant lutropin analogs

Asomi Sato, Burkhard Hirsch, T Sugahara et al. · Nature Biotechnology · 1997 · 44 citations

Protein Engineering, Bioconjugation, Synthetic Biology

Expression of biologically active fusion genes encoding the common α subunit and either the CGβ or FSHβ subunits: role of a linker sequence

T Sugahara, Peter D. J. Grootenhuis, Asomi Sato et al. · Molecular and Cellular Endocrinology · 1996 · 40 citations

Linker Sequence, Transcriptional Regulation, Protein Function +14