Matthias Gehringer

Selective JAK3 Inhibitors with a Covalent Reversible Binding Mode Targeting a New Induced Fit Binding Pocket

Michael Förster, A. Chaikuad, Silke M. Bauer et al. · Cell chemical biology · 2016 · 128 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

The Macrolide Toxin Mycolactone Promotes Bim-Dependent Apoptosis in Buruli Ulcer through Inhibition of mTOR

Raphael Bieri, Nicole Scherr, Marie‐Thérèse Ruf et al. · ACS Chemical Biology · 2017 · 77 citations

Life Sciences, Cell Biology, Pharmacology +17

Development, Optimization, and Structure–Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-<i>d</i>]pyrrolo[2,3-<i>b</i>]pyridine Scaffold

Michael Förster, A. Chaikuad, Teodor Dimitrov et al. · Journal of Medicinal Chemistry · 2018 · 59 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Silica-supported l-proline organocatalysts for asymmetric aldolisation

Alexandra Zamboulis, Nicolas J. Rahier, Matthias Gehringer et al. · Tetrahedron Asymmetry · 2009 · 46 citations

Natural Sciences, Chemistry, Inorganic Chemistry +5

Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes

Matthias Gehringer, Ellen Pfaffenrot, Silke M. Bauer et al. · ChemMedChem · 2014 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13