Oxidation of Cofilin Mediates T Cell Hyporesponsiveness under Oxidative Stress Conditions

Martin Klemke, Guido Wabnitz, Faustina Funke, +3

Immunity

Reductive StressRedox SignalingSignal TransductionBiochemistryCell Signaling +8

T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

Eddy Bruyns, Anne Marie‐Cardine, Henning Kirchgessner, +7

The Journal of Experimental Medicine

A functional complex is formed in human T lymphocytes between the protein tyrosine phosphatase CD45, the protein tyrosine kinase p56^lck and pp³², a possible common substrate

Burkhart Schraven, Henning Kirchgessner, Brigitte Gaber, +2

European Journal of Immunology

Molecular Cloning of SKAP55, a Novel Protein That Associates with the Protein Tyrosine Kinase p59 in Human T-lymphocytes

Anne Marie‐Cardine, Eddy Bruyns, Christoph Eckerskorn, +3

Journal of Biological Chemistry

ImmunologyMolecular BiologyCellular PhysiologySignaling PathwayReceptor Tyrosine Kinase +15

Mitochondrial translocation of oxidized cofilin induces caspase-independent necrotic-like programmed cell death of T cells

Guido Wabnitz, Catherine Goursot, Beate Jahraus, +5

Cell Death and Disease

InflammationMitophagySignal TransductionMitochondrial FunctionMitochondrial Translocation +13

SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation

Anne Marie‐Cardine, Henning Kirchgessner, Eddy Bruyns, +6

The Journal of Experimental Medicine

Sustained LFA‐1 cluster formation in the immune synapse requires the combined activities of <scp>L</scp>‐plastin and calmodulin

Guido Wabnitz, Philipp Lohneis, Henning Kirchgessner, +5

European Journal of Immunology

Cell AdhesionImmunologyMolecular BiologyAntigen ProcessingLfa‐1 Cluster Formation +18

LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes.

Burkhart Schraven, David S. Schoenhaut, Eddy Bruyns, +7

Journal of Biological Chemistry

T-regulatory CellImmunologyImmune RegulationImmunologic MechanismAntigen Processing +16

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

Henning Kirchgessner, Jes Dietrich, Jeanette Scherer, +7

The Journal of Experimental Medicine

Human T lymphocyte activation induces tyrosine phosphorylation of α‐tubulin and its association with the SH2 domain of the p59^fyn protein tyrosine kinase

Anne Marie‐Cardine, Henning Kirchgessner, Christoph Eckerskorn, +2

European Journal of Immunology