Irene Chau

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

Masoud Vedadi, Dalia Baršytė-Lovejoy, Feng Liu et al. · Nature Chemical Biology · 2011 · 527 citations

Signal Transduction, Cellular Enzymology, Biochemistry +12

Discovery of a 2,4-Diamino-7-aminoalkoxyquinazoline as a Potent and Selective Inhibitor of Histone Lysine Methyltransferase G9a

Feng Liu, Xin Chen, Abdellah Allali‐Hassani et al. · Journal of Medicinal Chemistry · 2009 · 236 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +17

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

Amy K. Wernimont, J.D. Artz, P.J. Finerty et al. · Nature Structural & Molecular Biology · 2010 · 235 citations · Full text

Protein Function, Molecular Physiology, Signal Transduction +12

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

Feng Liu, Xin Chen, Abdellah Allali‐Hassani et al. · Journal of Medicinal Chemistry · 2010 · 204 citations · Full text

Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5

Guillermo Senisterra, Hong Wu, Abdellah Allali‐Hassani et al. · Biochemical Journal · 2012 · 158 citations · Full text