Hermann C. Altmeppen

The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

Jan Wenzel, Josephine Lampe, Helge Müller‐Fielitz et al. · Nature Neuroscience · 2021 · 263 citations · Full text

Life Sciences, Cell Biology, Pathobiology +15

Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta‐mediated neurotoxicity

Clemens Falker, A. Hartmann, Inga Guett et al. · Journal of Neurochemistry · 2015 · 169 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Postnatal Disruption of the Disintegrin/Metalloproteinase ADAM10 in Brain Causes Epileptic Seizures, Learning Deficits, Altered Spine Morphology, and Defective Synaptic Functions

Johannes Prox, Christian Bernreuther, Hermann C. Altmeppen et al. · Journal of Neuroscience · 2013 · 127 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance

Michelle Rothaug, Friederike Zunke, Joseph R. Mazzulli et al. · Proceedings of the National Academy of Sciences · 2014 · 127 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Characterization of brain‐derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake

Santra Brenna, Hermann C. Altmeppen, Behnam Mohammadi et al. · Journal of Extracellular Vesicles · 2020 · 117 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14