Xuqin Chen

Induced expression of B7-H3 on the lung cancer cells and macrophages suppresses T-cell mediating anti-tumor immune response

Cheng Chen, Yu Shen, Qiu‐Xia Qu et al. · Experimental Cell Research · 2012 · 101 citations

Cancer Immunosurveillance, Medicine, T-regulatory Cell +10

B7-H3 Participates in the Development of Experimental Pneumococcal Meningitis by Augmentation of the Inflammatory Response via a TLR2-Dependent Mechanism

Xuqin Chen, Edel Quinn, Hong Ni et al. · The Journal of Immunology · 2012 · 44 citations

Microbial Pathogens, Innate Immune System, Immunology +24

Circulating B7-H3(CD276) Elevations in Cerebrospinal Fluid and Plasma of Children with Bacterial Meningitis

Xuqin Chen, Guangbo Zhang, Yan Li et al. · Journal of Molecular Neuroscience · 2008 · 31 citations · Full text

Medicine, Cerebrospinal Fluid, Immunology +3

B7-H3 Augments Inflammatory Responses and Exacerbates Brain Damage via Amplifying NF-κB p65 and MAPK p38 Activation during Experimental Pneumococcal Meningitis

Xuqin Chen, Yan Li, Siobhan Blankson et al. · PLoS ONE · 2017 · 29 citations · Full text

Inflammatory Lung Disease, Lung Inflammation, Innate Immune System +28

Activation of the TLR2-mediated downstream signaling pathways NF-κB and MAPK is responsible for B7-H3-augmented inflammatory response during S. pneumoniae infection

Xuqin Chen, Xiangying Meng, Niamh Foley et al. · Journal of Neuroimmunology · 2017 · 20 citations

Inflammation, Toll-like Receptors, Innate Immune System +12