Julia Dreisbach

In Vivo Dearomatization of the Potent Antituberculosis Agent BTZ043 via Meisenheimer Complex Formation

Viktor Krchňák, Anna Krchňáková, Sebastian Schieferdecker et al. · Angewandte Chemie International Edition · 2017 · 63 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043–02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial

Norbert Heinrich, Veronique de Jager, Julia Dreisbach et al. · The Lancet Microbe · 2025 · 25 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis

Andreas Römpp, Axel Treu, Julia Kokesch‐Himmelreich et al. · Nature Communications · 2025 · 15 citations · Full text

Medicine, Infectious Diseases, Pharmacology +14

Pharmacokinetics and Efficacy of the Benzothiazinone BTZ-043 against Tuberculous Mycobacteria inside Granulomas in the Guinea Pig Model

Emmelie Eckhardt, Yan Li, Svenja Mamerow et al. · Antimicrobial Agents and Chemotherapy · 2023 · 13 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Effect of seven anti-tuberculosis treatment regimens on sputum microbiome: a retrospective analysis of the HIGHRIF study 2 and PanACEA MAMS-TB clinical trials

Emmanuel Musisi, Adam J. Wyness, Sahar Eldirdiri et al. · The Lancet Microbe · 2023 · 10 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +14