Concepedia

Karen M. Brashear

KM

8

Publications

424

Citations

8

H-Index

1996

Active since

Affiliations

United States Military Academy(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Karen M. Brashear is an author at United States Military Academy specializing in medicine, drug discovery, and pharmacology.

Top concepts

Publications per year

1996–2009

8

Publications

8

Nonpeptide α<sub>v</sub>β<sub>3</sub> Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent α<sub>v</sub>β<sub>3</sub> Antagonist for the Prevention and Treatment of Osteoporosis

John H. Hutchinson, Wasyl Halczenko, Karen M. Brashear et al. · Journal of Medicinal Chemistry · 2003 · 96 citations · Full text

, , +17

Nonpeptide α<sub>v</sub>β<sub>3</sub> Antagonists. Part 11:  Discovery and Preclinical Evaluation of Potent α<sub>v</sub>β<sub>3</sub> Antagonists for the Prevention and Treatment of Osteoporosis

Paul J. Coleman, Karen M. Brashear, Ben Askew et al. · Journal of Medicinal Chemistry · 2004 · 79 citations · Full text

, , +16

Discovery of a Potent, CNS‐Penetrant Orexin Receptor Antagonist Based on an <i>N</i>,<i>N</i>‐Disubstituted‐1,4‐diazepane Scaffold that Promotes Sleep in Rats

David B. Whitman, Christopher D. Cox, Michael J. Breslin et al. · ChemMedChem · 2009 · 71 citations

Non-Peptide Glycoprotein IIb/IIIa Antagonists. 11. Design and <i>in Vivo</i> Evaluation of 3,4-Dihydro-1(1<i>H</i>)-isoquinolinone-Based Antagonists and Ethyl Ester Prodrugs

John H. Hutchinson, Jacquelynn J. Cook, Karen M. Brashear et al. · Journal of Medicinal Chemistry · 1996 · 64 citations · Full text

<i>N</i>-Arylpiperazinone Inhibitors of Farnesyltransferase:  Discovery and Biological Activity

Theresa M. Williams, Jeffrey M. Bergman, Karen M. Brashear et al. · Journal of Medicinal Chemistry · 1999 · 45 citations · Full text

, , +18

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