Aloysus K. Lawong

Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in <i>Plasmodium falciparum</i> that Confer <i>in Vitro</i> Resistance to the Clinical Candidate DSM265

John White, Satish K. Dhingra, Xiaoyi Deng et al. · ACS Infectious Diseases · 2018 · 55 citations · Full text

Antiparasitic Agent, Genetics, Malaria +18

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Michael Palmer, Xiaoyi Deng, Shawn Watts et al. · Journal of Medicinal Chemistry · 2021 · 44 citations · Full text

Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in <i>Plasmodium falciparum</i>

Aloysus K. Lawong, Suraksha Gahalawat, John Okombo et al. · Journal of Medicinal Chemistry · 2021 · 20 citations · Full text

Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria

Aloysus K. Lawong, Suraksha Gahalawat, S. Ray et al. · Cell chemical biology · 2024 · 13 citations · Full text

Fast-Killing Tyrosine Amide (( <i>S</i> )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( <i>Pf</i> CARL)

Leah S. Imlay, Aloysus K. Lawong, Suraksha Gahalawat et al. · ACS Infectious Diseases · 2023 · 10 citations · Full text