Mitchell L. Leibowitz

Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing

Mitchell L. Leibowitz, Stamatis Papathanasiou, Phillip A. Doerfler et al. · Nature Genetics · 2021 · 535 citations · Full text

Crispr–cas9 Genome Editing, Genetics, Molecular Biology +5

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

Aaron R. Quinlan, Royden A. Clark, Svetlana Sokolova et al. · Genome Research · 2010 · 298 citations · Full text

Structural Variation, Genetics, Genomic Mechanism +22

Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms

Ankit Malhotra, Michael Lindberg, Gregory G. Faust et al. · Genome Research · 2013 · 177 citations · Full text

Engineering, Complex Rearrangements, Genetics +20

Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing

Stamatis Papathanasiou, Styliani Markoulaki, Logan J. Blaine et al. · Nature Communications · 2021 · 134 citations · Full text

Genome Sequencing of Mouse Induced Pluripotent Stem Cells Reveals Retroelement Stability and Infrequent DNA Rearrangement during Reprogramming

Aaron R. Quinlan, Michael J. Boland, Mitchell L. Leibowitz et al. · Cell stem cell · 2011 · 115 citations · Full text

Infrequent Dna Rearrangement, Lineage Plasticity, Induced Pluripotent Stem Cell +10