Lawrence E. Lesheski

Palladium-catalyzed intermolecular vinylic arylation of cycloalkenes. Applications to the synthesis of quinolone antibacterials

Edgardo Laborde, Lawrence E. Lesheski, John S. Kiely · Tetrahedron Letters · 1990 · 32 citations

Engineering, Organic Chemistry, Catalysis +5

Quinolone antibacterials: synthesis and biological activity of carbon isosteres of the 1-piperazinyl and 3-amino-1-pyrrolidinyl side chains

Edgardo Laborde, John S. Kiely, Townley P. Culbertson et al. · Journal of Medicinal Chemistry · 1993 · 26 citations · Full text

Combinatorial Chemistry, Antibacterial Activity, Organic Chemistry +18

Quinolone antibacterials: preparation and activity of bridged bicyclic analogues of the C7-piperazine

John S. Kiely, Marland P. Hutt, Townley P. Culbertson et al. · Journal of Medicinal Chemistry · 1991 · 20 citations

Synthesis of 7‐(alkenyl, cycloalkenyl, and 1,2,3,6‐tetrahydro‐4‐pyridinyl)quinolones

John S. Kiely, Edgardo Laborde, Lawrence E. Lesheski et al. · Journal of Heterocyclic Chemistry · 1991 · 17 citations

A general method for the preparation of 2‐substituted‐4‐oxo‐3‐quinolinecarboxylic acids

John S. Kiely, Suchin Huang, Lawrence E. Lesheski · Journal of Heterocyclic Chemistry · 1989 · 16 citations

Diversity Oriented Synthesis, Pharmaceutical Chemistry, Engineering +12