Michael F. Hirshman

Role of AMP-activated protein kinase in mechanism of metformin action

Gaochao Zhou, Robert P. Myers, Ying Li et al. · Journal of Clinical Investigation · 2001 · 5.3K citations

Brown adipose tissue regulates glucose homeostasis and insulin sensitivity

Kristin I. Stanford, Roeland J.W. Middelbeek, Kristy L. Townsend et al. · Journal of Clinical Investigation · 2012 · 1.2K citations · Full text

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

Manisha Sinha, Young C. Jang, Juhyun Oh et al. · Science · 2014 · 818 citations · Full text

Mechanobiology, Regenerative Medicine, Inflammation +14

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

Nicolas Musi, Michael F. Hirshman, Jonas Nygren et al. · Diabetes · 2002 · 800 citations · Full text

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance

Ariel Zisman, Odile D. Peroni, E. Dale Abel et al. · Nature Medicine · 2000 · 751 citations

Insulin Resistance, Metabolic Syndrome, Muscle Causes +15