Alex J. Buckmelter

Pyrazolopyridine Inhibitors of B-Raf^V600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors

Steve Wenglowsky, Li Ren, Kateri A. Ahrendt et al. · ACS Medicinal Chemistry Letters · 2011 · 66 citations · Full text

Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships

Steve Wenglowsky, Kateri A. Ahrendt, Alex J. Buckmelter et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 55 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +5

Potent and Selective Aminopyrimidine-Based B-Raf Inhibitors with Favorable Physicochemical and Pharmacokinetic Properties

Simon Mathieu, Stefan Gradl, Li Ren et al. · Journal of Medicinal Chemistry · 2012 · 47 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +19

The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors

Alex J. Buckmelter, Li Ren, Ellen R. Laird et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 26 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-RafV600E kinase with favorable physicochemical and pharmacokinetic properties

Li Ren, Ellen R. Laird, Alex J. Buckmelter et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 24 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +13