John Lyle

Real-Time DNA Sequencing from Single Polymerase Molecules

John Eid, Adrian Fehr, Jeremy Gray et al. · Science · 2008 · 3.8K citations

Life Sciences, Molecular Biology, Dna Replication +12

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial

Mark Yarchoan, Edward Gane, Thomas U. Marron et al. · Nature Medicine · 2024 · 218 citations · Full text

Medicine, Oncology, Pharmacology +17

A deletion mutant in the human cytomegalovirus gene encoding IE1(491aa) is replication defective due to a failure in autoregulation.

Edward S. Mocarski, George Kemble, John Lyle et al. · Proceedings of the National Academy of Sciences · 1996 · 215 citations

Life Sciences, Genetics, Molecular Biology +15

Visualization and Functional Analysis of RNA-Dependent RNA Polymerase Lattices

John Lyle, Esther Bullitt, Kurt Bienz et al. · Science · 2002 · 164 citations

Life Sciences, Microbiology, Molecular Biology +17

Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma

James R. Black, Gábor Bartha, Charles W. Abbott et al. · Nature Medicine · 2025 · 83 citations · Full text

Medicine, Oncology, Pathology +17