Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages

Jessica Hoppstädter, Britta Diesel, Robert Zarbock, +8

Respiratory Research

Saccharomyces cerevisiae: a versatile eukaryotic system in virology

Rui Pedro Galão, Nicoletta Scheller, Isabel Alves‐Rodrigues, +3

Microbial Cell Factories

Viral ReplicationMolecular VirologyCell DivisionSaccharomyces CerevisiaeNeurovirology +11

A genetic-algorithm approach to simulating human immunodeficiency virus evolution reveals the strong impact of multiply infected cells and recombination

Gennady Bocharov, Neville J. Ford, J. H. Edwards, +3

Journal of General Virology

Viral ReplicationEngineeringGeneticsArtificial Immune SystemMolecular Biology +17

Delivery of functional DNA and messenger RNA to mammalian phagocytic cells by recombinant yeast

Barbara Walch, Tanja Breinig, Manfred Schmitt, +1

Gene Therapy

Recombinant YeastImmunologyGene DeliveryGene VectorFunctional Dna +4

Uptake of various yeast genera by antigen-presenting cells and influence of subcellular antigen localization on the activation of ovalbumin-specific CD8 T lymphocytes

Silvia B. Bazan, Gernot Geginat, Tanja Breinig, +2

Vaccine

Autoimmune DiseaseAdaptive Immune SystemSubcellular Antigen LocalizationImmunologyImmunodominance +7

Heat treatment improves antigen-specific T cell activation after protein delivery by several but not all yeast genera

Silvia B. Bazan, Tanja Breinig, Manfred Schmitt, +1

Vaccine

Adaptive Immune SystemT-regulatory CellImmunologyAntigen ProcessingAutoimmunity +7

T cell activation on a single-cell level in dielectrophoresis-based microfluidic devices

Michael Kirschbaum, Magnus S. Jaeger, Tim Schenkel, +3

Journal of Chromatography A

T Cell ActivationEngineeringMicrofabricationAnalytical MicrosystemsDielectrophoresis-based Microfluidic Devices +8

The Autographa californica nuclear polyhedrosis virus AcNPV induces functional maturation of human monocyte-derived dendritic cells

Alexandra Schütz, Nicoletta Scheller, Tanja Breinig, +1

Vaccine

Viral ReplicationMolecular VirologyViral PathogenesisImmunologyVirology +5

Cross-presentation of HLA class I epitopes from influenza matrix protein produced in Saccharomyces cerevisiae

Andreas Wadle, Gerhard Held, Frank Neumann, +8

Vaccine

VaccinationSaccharomyces CerevisiaeHla ImmunogeneticsPathogenesisImmunology +10

Exploiting the Yeast L-A Viral Capsid for the In Vivo Assembly of Chimeric VLPs as Platform in Vaccine Development and Foreign Protein Expression

Frank Powilleit, Tanja Breinig, Manfred Schmitt

PLoS ONE

Viral ReplicationEngineeringSynthetic VirologyImmunologyMolecular Biology +16