Christina Gamba‐Vitalo

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

Teresa Coelho, David Adams, Ana Silva et al. · New England Journal of Medicine · 2013 · 961 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +15

First-in-Humans Trial of an RNA Interference Therapeutic Targeting VEGF and KSP in Cancer Patients with Liver Involvement

Josep Tabernero, Geoffrey I. Shapiro, Patricia LoRusso et al. · Cancer Discovery · 2013 · 699 citations

Pharmacy, Oncology, Pharmaceutics +17

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Maria Frank-Kamenetsky, Aldo Grefhorst, Norma N. Anderson et al. · Proceedings of the National Academy of Sciences · 2008 · 639 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

Akin Akinc, Michael S. Goldberg, June Qin et al. · Molecular Therapy · 2009 · 349 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

A status report on RNAi therapeutics

Akshay Vaishnaw, Jared Gollob, Christina Gamba‐Vitalo et al. · Silence · 2010 · 294 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15