Zhenfang Du

Epigenetic inactivation of the CpG demethylase TET1 as a DNA methylation feedback loop in human cancers

Lili Li, Chen Li, Haitao Mao et al. · Scientific Reports · 2016 · 126 citations · Full text

Medicine, Cancer Biology, Molecular Biology +17

On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation

Benjamin P. Brown, Yunkai Zhang, David Westover et al. · Clinical Cancer Research · 2019 · 107 citations · Full text

Medicine, Oncology, Pharmacology +17

Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting

Zhenfang Du, Benjamin P. Brown, Soyeon Kim et al. · Nature Communications · 2021 · 71 citations · Full text

Medicine, Molecular Biology, Oncology +17

Characterization of the Nasopharyngeal Carcinoma Methylome Identifies Aberrant Disruption of Key Signaling Pathways and Methylated Tumor Suppressor Genes

Lili Li, Yuan Zhang, Yichao Fan et al. · Epigenomics · 2014 · 66 citations

Life Sciences, Genetics, Oncology +17

Tumor suppressive BTB/POZ zinc-finger protein ZBTB28 inhibits oncogenic BCL6/ZBTB27 signaling to maintain p53 transcription in multiple carcinogenesis

Tingxiu Xiang, Jun Tang, Lili Li et al. · Theranostics · 2019 · 52 citations · Full text

Medicine, Cancer Biology, Oncology +17