Fumito Shimoma

Synthesis of anilino-monoindolylmaleimides as potent and selective PKCβ inhibitors

Masahiro Tanaka, Shoichi Sagawa, Jun‐ichi Hoshi et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 61 citations · Full text

Pharmacy, Chemistry, Pharmacology +8

Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCβ-selective inhibitors

Masahiro Tanaka, Shoichi Sagawa, Jun‐ichi Hoshi et al. · Bioorganic & Medicinal Chemistry · 2006 · 44 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthetic Method and Biological Activities of <i>cis</i>-Fused α-Methylene γ-Lactones

Yohsuke Higuchi, Fumito Shimoma, Masayoshi Ando · Journal of Natural Products · 2003 · 36 citations

Agriculture, Biochemistry, Food Chemistry +8

A Novel Synthetic Method of the (±)-(3aα,8aα)-Ethyl 8β-Hydroxy-6β-methyl-2-oxooctahydro-2<i>H</i>-cyclohepta[<i>b</i>]furan-3α- carboxylate and Its Chemical Transformation to (±)-(3aα,8aα)-3α,6β-Dimethyl-3,3a,4,5,6,8a-hexahydro-2<i>H</i>- cyclohepta[<i>b</i>]furan-2-one, (+)- and (−)-7β-(2-Acetoxy-1α-methylethyl)-4β-methyl-2-cyclohepten-1β-ol, and (+)- and (−)-7β-(2-Acetoxy-1α-methylethyl)-4β-methyl-2-cyclohepten-1-one. Possible Common Synthetic Intermediates for Pseudoguaianolides, 4,5-Secopseudoguaianolides, Guaianolides, 4,5-Secoguaianolides, and Octalactins

Fumito Shimoma, Haruhiko Kusaka, Katsuaki Wada et al. · The Journal of Organic Chemistry · 1998 · 32 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Enantioselective Total Syntheses of (−)-7β<i>H</i>-Eudesmane-4α,11-diol and (+)-<i>ent</i>-7β<i>H</i>-Eudesmane-4α,11-diol

Fumito Shimoma, Hisao Kondo, Saori Yuuya et al. · Journal of Natural Products · 1998 · 19 citations

Natural Sciences, Biochemistry, Chemistry +9