Paul W. Hastwell

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

David Kirkland, Stefan Pfuhler, David Tweats et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 437 citations

Pharmacy, Toxicology, Good Laboratory Practice +12

High-specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay

Paul W. Hastwell, Li-Leng Chai, Kevin J. Roberts et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2006 · 168 citations

Pharmacy, Cell Biology, Toxicology +8

Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay

Paul W. Hastwell, Thomas W. Webster, Matthew Tate et al. · Mutagenesis · 2009 · 51 citations · Full text

Pharmacy, Pharmacology, Toxicology +14

Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method

Nicholas Billinton, Paul W. Hastwell, D. Beerens et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2008 · 41 citations

Pharmacy, Toxicology, Analytical Toxicology +12

Genetic modification and variations in solvent increase the sensitivity of the yeast RAD54-GFP genotoxicity assay

L Walsh, Paul W. Hastwell, Patrick Keenan et al. · Mutagenesis · 2005 · 25 citations · Full text

Pharmacy, Molecular Biology, Toxicology +17