Paul W. Hastwell

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop

David Kirkland, Stefan Pfuhler, David Tweats et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2007 · 429 citations

Animal Testing, Veterinary Science, Toxicology Testing +7

High-specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay

Paul W. Hastwell, Li-Leng Chai, Kevin J. Roberts et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2006 · 168 citations

Immunotoxicology, Medicine, High-sensitivity Genotoxicity Assessment +9

Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP ‘GreenScreen HC’ genotoxicity assay

Paul W. Hastwell, Thomas W. Webster, Matthew Tate et al. · Mutagenesis · 2009 · 51 citations · Full text

Greenscreen Hc, Pharmaceutical Science, Pharmaceutical Research +15

Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method

Nicholas Billinton, Paul W. Hastwell, D. Beerens et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2008 · 41 citations

Enabling Study, Cancer Screening, Medicine +9

Genetic modification and variations in solvent increase the sensitivity of the yeast RAD54-GFP genotoxicity assay

L Walsh, Paul W. Hastwell, Patrick Keenan et al. · Mutagenesis · 2005 · 25 citations · Full text