Zuzana Pokorná

Clinically Translatable Prevention of Anthracycline Cardiotoxicity by Dexrazoxane Is Mediated by Topoisomerase II Beta and Not Metal Chelation

Eduard Jirkovský, Anna Jirkovská, Hana Bavlovič Piskáčková et al. · Circulation Heart Failure · 2021 · 58 citations · Full text

Medicine, Cardiology, Pharmacology +17

Pharmacokinetics of the Cardioprotective Drug Dexrazoxane and Its Active Metabolite ADR-925 with Focus on Cardiomyocytes and the Heart

Eduard Jirkovský, Anna Jirkovská, Jan Bureš et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 22 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane

Olga Lenčová-Popelová, Eduard Jirkovský, Hana Jansová et al. · Journal of Molecular and Cellular Cardiology · 2015 · 21 citations

Medicine, Cardiology, Pharmacology +16

Investigation of Structure-Activity Relationships of Dexrazoxane Analogs Reveals Topoisomerase IIβ Interaction as a Prerequisite for Effective Protection against Anthracycline Cardiotoxicity

Petra Kollárová-Brázdová, Anna Jirkovská, Galina Karabanovich et al. · Journal of Pharmacology and Experimental Therapeutics · 2020 · 20 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

<i>In vitro</i> and <i>in vivo</i> investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline

Zuzana Pokorná, Eduard Jirkovský, Markéta Hlaváčková et al. · Clinical Science · 2019 · 14 citations

Medicine, Cardiology, Pharmacology +17