Can E. Senkal

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

R. David Sentelle, Can E. Senkal, Wenhui Jiang et al. · Nature Chemical Biology · 2012 · 517 citations

Life Sciences, Biochemistry, Cell Biology +12

Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis

Sahar A. Saddoughi, Salih Gencer, Yuri K. Peterson et al. · EMBO Molecular Medicine · 2012 · 265 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Antiapoptotic roles of ceramide‐synthase‐6‐generated C ₁₆ ‐ceramide <i>via</i> selective regulation of the ATF6/ CHOP arm of ER‐stress‐response pathways

Can E. Senkal, Suriyan Ponnusamy, Jacek Bielawski et al. · The FASEB Journal · 2009 · 250 citations · Full text

Life Sciences, Cell Biology, Oncology +9

Ceramide Is Metabolized to Acylceramide and Stored in Lipid Droplets

Can E. Senkal, Mohamed Salama, Ashley J. Snider et al. · Cell Metabolism · 2017 · 228 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +11

Defects in Cell Growth Regulation by C18:0-Ceramide and Longevity Assurance Gene 1 in Human Head and Neck Squamous Cell Carcinomas

Serap Köybaşı, Can E. Senkal, Kamala Sundararaj et al. · Journal of Biological Chemistry · 2004 · 226 citations · Full text

Medicine, Cell Biology, Oncology +15