Frank J. Poelwijk

Mutation effects predicted from sequence co-variation

Thomas A. Hopf, John Ingraham, Frank J. Poelwijk et al. · Nature Biotechnology · 2017 · 871 citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Empirical fitness landscapes reveal accessible evolutionary paths

Frank J. Poelwijk, Daniel J. Kiviet, Daniel Weinreich et al. · Nature · 2007 · 613 citations

Life Sciences, Biology, Evolutionary Biology +13

The spatial architecture of protein function and adaptation

Richard N. McLaughlin, Frank J. Poelwijk, Arjun S. Raman et al. · Nature · 2012 · 477 citations

Life Sciences, Biochemistry, Molecular Biology +14

Illuminating protein space with a programmable generative model

John Ingraham, Max Baranov, Zak Costello et al. · Nature · 2023 · 403 citations · Full text

Life Sciences, Bioinformatics, Materials Science +17

Quantification of the effect of mutations using a global probability model of natural sequence variation

Thomas A. Hopf, John Ingraham, Frank J. Poelwijk et al. · arXiv (Cornell University) · 2015 · 289 citations · Full text

Life Sciences, Evolutionary Biology, Computational Biology +7