Frank J. Poelwijk

Mutation effects predicted from sequence co-variation

Thomas A. Hopf, John Ingraham, Frank J. Poelwijk et al. · Nature Biotechnology · 2017 · 833 citations · Full text

Mutation-based Testing, Medicine, Genetics +4

Empirical fitness landscapes reveal accessible evolutionary paths

Frank J. Poelwijk, Daniel J. Kiviet, Daniel Weinreich et al. · Nature · 2007 · 590 citations

Biology, Evolution Strategy, Fitness +5

The spatial architecture of protein function and adaptation

Richard N. McLaughlin, Frank J. Poelwijk, Arjun S. Raman et al. · Nature · 2012 · 472 citations

Biology, Protein Function, Protein Folding +4

Illuminating protein space with a programmable generative model

John Ingraham, Max Baranov, Zak Costello et al. · Nature · 2023 · 345 citations · Full text

Quantification of the effect of mutations using a global probability model of natural sequence variation

Thomas A. Hopf, John Ingraham, Frank J. Poelwijk et al. · arXiv (Cornell University) · 2015 · 289 citations · Full text

Genetics, Point Mutants, Molecular Biology +24