Edward R. Bacon

Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis

Rabindranath Tripathy, Alyssa Reiboldt, Patricia A. Messina et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 104 citations · Full text

Medicinal Chemistry, Drug Target, Medicine +9

1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors

Rabindranath Tripathy, Arup K. Ghose, J. B. Singh et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 89 citations · Full text

Medicinal Chemistry, Medicine, Rational Drug Design +5

Synthesis of 7-azaindole and 7-azaoxindole derivatives through a palladium-catalyzed cross-coupling reaction

Virendra Kumar, John A. Dority, Edward R. Bacon et al. · The Journal of Organic Chemistry · 1992 · 69 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +11

Discovery and Characterization of 6-{4-[3-(<i>R</i>)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2<i>H</i>-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H₃Receptor Inverse Agonist

Robert L. Hudkins, Rita Raddatz, Ming Tao et al. · Journal of Medicinal Chemistry · 2011 · 68 citations · Full text

CEP-26401 (Irdabisant), a Potent and Selective Histamine H3 Receptor Antagonist/Inverse Agonist with Cognition-Enhancing and Wake-Promoting Activities

Rita Raddatz, Robert L. Hudkins, Joanne R. Mathiasen et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 58 citations