Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration

Kazuhisa Ishida, Kaoru Yamada, Risa Nishiyama, +5

The Journal of Experimental Medicine

Glymphatic SystemImmunologyNeurochemical BiomarkersCytoskeletonTau Aggregation +14

Detailed Characterization of Neuroprotection by a Rescue Factor Humanin against Various Alzheimer's Disease-Relevant Insults

Yuichi Hashimoto, Takako Niikura, Yuko Ito, +6

Journal of Neuroscience

Cell DeathNeurochemical BiomarkersHn Derivative PeptidesAmyloid Precursor ProteinOxidative Stress +17

Orexin Receptor Type-1 Couples Exclusively to Pertussis Toxin-Insensitive G-Proteins, While Orexin Receptor Type-2 Couples to Both Pertussis Toxin-Sensitive and -Insensitive G-Proteins

Yun Zhu, Yoshihiro Miwa, Akihiro Yamanaka, +5

Journal of Pharmacological Sciences

Cloning and characterization of a novel endothelin receptor subtype in the avian class

Laure Lecoin, Takeshi Sakurai, Minh-Triet Ngo, +3

Proceedings of the National Academy of Sciences

<i>TSHR</i>Mutations as a Cause of Congenital Hypothyroidism in Japan: A Population-Based Genetic Epidemiology Study

Satoshi Narumi, Koji Muroya, Yoichiro Abe, +4

The Journal of Clinical Endocrinology & Metabolism

Molecular Identification of Guanine-Nucleotide-Binding Regulatory Proteins which Couple to Endothelin Receptors

Miho Takigawa, Takeshi Sakurai, Yoshitoshi Kasuya, +2

European Journal of Biochemistry

Molecular BiologyGuanine-nucleotide-binding Regulatory ProteinsCellular PhysiologyReceptor Tyrosine KinaseEndocytic Pathway +17

Neuronal Apoptosis by Apolipoprotein E4 through Low-Density Lipoprotein Receptor-Related Protein and Heterotrimeric GTPases

Yuichi Hashimoto, Hong Jiang, Takako Niikura, +6

Journal of Neuroscience

ApoptosisCell DeathApolipoprotein E4GliomaHeat-inactivated Ptx +19

Insulin-Like Growth Factor I (IGF-I) Protects Cells from Apoptosis by Alzheimer's V642I Mutant Amyloid Precursor Protein through IGF-I Receptor in an IGF-Binding Protein-Sensitive Manner

Takako Niikura, Yuichi Hashimoto, Takashi Okamoto, +8

Journal of Neuroscience

Igf-binding Protein-sensitive MannerCell DeathNeurochemical BiomarkersAmyloid Precursor ProteinIgf-i Receptor +17

Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

Hiromu Monai, Xiaowen Wang, Kazuko Yahagi, +8

Proceedings of the National Academy of Sciences

Severely exacerbated neuromyelitis optica rat model with extensive astrocytopathy by high affinity anti-aquaporin-4 monoclonal antibody

Kazuhiro Kurosawa, Tatsuro Misu, Yoshiki Takai, +10

Acta Neuropathologica Communications