Genome-Wide Profiling of p63 DNA–Binding Sites Identifies an Element that Regulates Gene Expression during Limb Development in the 7q21 SHFM1 Locus

Evelyn N. Kouwenhoven, Simon J. van Heeringen, Juan J. Tena, +22

PLoS Genetics

GeneticsShfm1 LocusGenomic MechanismLimb DevelopmentDisease Gene Identification +17

Transcription factor p63 bookmarks and regulates dynamic enhancers during epidermal differentiation

Evelyn N. Kouwenhoven, Martin Oti, Hanna Niehues, +5

EMBO Reports

De Novo Mutations in the Genome Organizer CTCF Cause Intellectual Disability

Anne Gregor, Martin Oti, Evelyn N. Kouwenhoven, +11

The American Journal of Human Genetics

Genetic DisorderGeneticsFragile X SpectrumDisease Gene IdentificationGenomics +3

Prediction of Human Disease Genes by Human-Mouse Conserved Coexpression Analysis

Ugo Ala, Rosario M. Piro, Elena Grassi, +5

PLoS Computational Biology

Phenome connections

Martin Oti, Martijn A. Huynen, Han G. Brunner

Trends in Genetics

CTCF-mediated chromatin loops enclose inducible gene regulatory domains

Martin Oti, Jonas Falck, Martijn A. Huynen, +1

BMC Genomics

Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enhancer Landscape

Jieqiong Qu, Sabine E.J. Tanis, Jos P.H. Smits, +8

Cell Reports

DermatologyCell SpecializationEpigeneticsTumor BiologyTranscriptional Regulation +14

Systematic analysis of copy number variants of a large cohort of orofacial cleft patients identifies candidate genes for orofacial clefts

Federica Conte, Martin Oti, Jill Dixon, +3

Human Genetics

Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila

Merel A.W. Oortveld, Shivakumar Keerthikumar, Martin Oti, +15

PLoS Genetics

Developmental BiologyDrosophila EyeGeneticsFunctional ConnectivityGene Structure +11

TAF5L and TAF6L Maintain Self-Renewal of Embryonic Stem Cells via the MYC Regulatory Network

Davide Seruggia, Martin Oti, Pratibha Tripathi, +13

Molecular Cell

Lineage PlasticityDevelopmental BiologyCell RegulationMedicineMyc Regulatory Network +9