Alan Huett

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

John D. Rioux, Ramnik J. Xavier, Kent D. Taylor et al. · Nature Genetics · 2007 · 1.7K citations · Full text

Genome-wide Association Study, Cell Autophagy, Disease Mechanism +10

Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

Steven A. McCarroll, Alan Huett, Petric Kuballa et al. · Nature Genetics · 2008 · 657 citations · Full text

Disease Mechanism, Genetics, Pathogenesis +8

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

Petric Kuballa, Alan Huett, John D. Rioux et al. · PLoS ONE · 2008 · 326 citations · Full text

Genetics, Immunology, Genetic Epidemiology +18

Crohn's disease-associated adherent-invasive <i>E.âcoli</i> are selectively favoured by impaired autophagy to replicate intracellularly

Pierre Lapaquette, Anne-Lise Glasser, Alan Huett et al. · Cellular Microbiology · 2009 · 300 citations · Full text

Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity

Aylwin Ng, Jason M. Eisenberg, Robert J. W. Heath et al. · Proceedings of the National Academy of Sciences · 2010 · 254 citations · Full text

Engineering, Genetics, Innate Immune System +23