Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct

Uma Mahesh Gundra, Natasha Girgis, Dominik Rückerl, +9

Blood

Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cells

Upal Basu-Roy, N. Sumru Bayın, Kirk Rattanakorn, +4

Nature Communications

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas

Upal Basu-Roy, E Seo, Lalitha Ramanathapuram, +5

Oncogene

Tumor-initiating CellsMedicineCancer Cell BiologyCancer BiologyCell Biology +1

SOX2 Regulates YAP1 to Maintain Stemness and Determine Cell Fate in the Osteo-Adipo Lineage

Eunjeong Seo, Upal Basu-Roy, Preethi H. Gunaratne, +4

Cell Reports

The transcription factor Sox2 is required for osteoblast self-renewal

Upal Basu-Roy, Damien Ambrosetti, Rebecca Favaro, +3

Cell Death and Differentiation

Regenerative MedicineTranscriptional RegulationTranscription Factor Sox2Bone RepairMedicine +2

Angiotensin receptors and β-catenin regulate brain endothelial integrity in malaria

Julio Gallego‐Delgado, Upal Basu-Roy, Maureen Ty, +11

Journal of Clinical Investigation

Endothelial CellsMalariaImmunologyCell DeathCerebral Vascular Regulation +19

Distinct Functions of Sox2 Control Self-Renewal and Differentiation in the Osteoblast Lineage

Eunjeong Seo, Upal Basu-Roy, Jiří Zavadil, +2

Molecular and Cellular Biology

Osteoblast LineageSox2 DeletionOsteogenesisStem Cell BiologySox2 Inactivation +24

miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer

Yinghong Pan, Gordon Robertson, Lykke Pedersen, +25

Oncotarget

PPARγ agonists promote differentiation of cancer stem cells by restraining YAP transcriptional activity

Upal Basu-Roy, Eugenia J. Han, Kirk Rattanakorn, +9

Oncotarget

Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole

Sally Liao, Yuleisy Ruiz, Hira Gulzar, +9

PLoS ONE

Cell DeathOsteosarcoma CellsCancer BiologyTumor BiologyGlutamate Release +16