FGF23 induces left ventricular hypertrophy

Christian Faul, Ansel P. Amaral, Behzad N. Oskouei, +32

Journal of Clinical Investigation

HypertensionHeart FailurePathologyCardiovascular FunctionMetabolic Syndrome +16

Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular Hypertrophy

Alexander Grabner, Ansel P. Amaral, Karla Schramm, +28

Cell Metabolism

Cardiac MuscleCardiomyopathyHeart FailurePhysiologyMedicine +3

COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

Saskia F. Heeringa, Gil Chernin, Moumita Chaki, +52

Journal of Clinical Investigation

Angiotensin II Contributes to Podocyte Injury by Increasing TRPC6 Expression via an NFAT-Mediated Positive Feedback Signaling Pathway

Tom Nijenhuis, Alexis Sloan, Joost G.J. Hoenderop, +14

American Journal Of Pathology

InflammationCytokineSignal TransductionMolecular PhysiologyAutoimmune Disease +11

Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury

Christopher E. Pedigo, Gloria Michelle Ducasa, Farah Leclercq, +22

Journal of Clinical Investigation

Vascular DiseaseImmunologyCell DeathLocal TnfNephrology +17

ATP-binding cassette A1 deficiency causes cardiolipin-driven mitochondrial dysfunction in podocytes

Gloria Michelle Ducasa, Alla Mitrofanova, Shamroop Kumar Mallela, +22

Journal of Clinical Investigation

Lipid PeroxidationCellular PhysiologyAbca1 ExpressionOxidative StressMetabolic Syndrome +16

SMPDL3b modulates insulin receptor signaling in diabetic kidney disease

Alla Mitrofanova, Shamroop Kumar Mallela, Gloria Michelle Ducasa, +23

Nature Communications

Hydroxypropyl-β-cyclodextrin protects from kidney disease in experimental Alport syndrome and focal segmental glomerulosclerosis

Alla Mitrofanova, Judith Molina, Javier Varona Santos, +18

Kidney International

Glomerular DiseaseGlomerulonephritisUrologyRenal DiseaseHydroxypropyl-β-cyclodextrin Protects +13

Activation of Stimulator of IFN Genes (STING) Causes Proteinuria and Contributes to Glomerular Diseases

Alla Mitrofanova, Antonio Miguel Fontanella, Matthew Tolerico, +18

Journal of the American Society of Nephrology

Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease

Matthew B. Wright, Javier Varona Santos, Christian Kemmer, +18

Nature Communications