Sophie Jallat

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo

Melissa A. Rosenfeld, Wolfgang Siegfried, Kunihiko Yoshimura et al. · Science · 1991 · 743 citations

Medicine, Molecular Biology, Molecular Genetics +15

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Wilfried Dalemans, Pascal Barbry, Guy Champigny et al. · Nature · 1991 · 700 citations

Natural Sciences, Genetics, Molecular Genetics +13

cDNA cloning and expression of a hamster α‐thrombin receptor coupled to Ca²⁺ mobilization

Ulla Rasmussen, Valérie Vouret-Craviari, Sophie Jallat et al. · FEBS Letters · 1991 · 465 citations

Life Sciences, Biochemistry, Molecular Biology +17

Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.

Richard C. Hubbard, Fumitaka Ogushi, G A Fells et al. · Journal of Clinical Investigation · 1987 · 157 citations · Full text

Life Sciences, Immunology, Immunophysiology +10

Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium.

C.S. Chu, Bruce C. Trapnell, James J. Murtagh et al. · The EMBO Journal · 1991 · 137 citations · Full text

Life Sciences, Genetics, Molecular Genetics +9